Aldactazide (Spironolactone/Hydrochlorothiazide) and/or equivalents

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• This item requires a prescription from your doctor


• What is a Generic?

Description of Aldactazide

Aldactazide is a combination of two generic drugs: Hydrochlorothiazide and Spironolactone. Hydrochlorothiazide belongs to the class of thiazide diuretics, and Spironolactone is one of the potassium-sparing diuretics. Apart from these two ingredients, the medicine also contains some inactive ingredients including titanium dioxide, povidone, polyethylene glycol, magnesium stearate, iron oxide, hypromellose, hydroxypropyl cellulose, corn starch, calcium sulfate and flavor. You can buy Aldactazide in the form of oral tablets, available in 25/25 and 50/50 strengths.

Indications & Dosage of Aldactazide

Aldactazide is used for treating fluid retention or edema in patients suffering from a kidney disorder (nephrotic syndrome), cirrhosis of liver or congestive heart failure. In some cases, this drug can also be used for treating high blood pressure or hypertension. Hydrochlorothiazide works by preventing the patients’ body from absorbing excess salt, and Spironolactone works by keeping potassium levels from becoming too low.

For treating edema, the patients will receive Aldactazide 100mg per day, taken as a single dose or as divided doses. For treating hypertension, you will be advised to take Aldactazide 50mg to 100mg per day.

Side Effects & Interactions of Aldactazide

Aldactazide patients can commonly experience mild vomiting, nausea, dizziness, gas, headache, stomach pain or skin rash. These are mild side effects of the drug and subside on their own as your body becomes tolerant to it. However, inform your doctor at once if any of these persist or worsen. Also seek medical attention immediately if you develop any serious side effects of the drug. Symptoms of such side effects include:

• Vision problems, eye pain
• Numbness or tingling
• Uneven, slow or fast heartbeat
• Muscle weakness or pain
• Drowsiness, restlessness or lightheadedness
• Decreased or stopped urination
• Shallow breathing
• Upper stomach pain, nausea, loss of appetite, itching, dark urine, and jaundice, clay-colored stools, yellowing of the eyes or skin
• Confusion, tremors
• Severe skin reactions, identified by swelling of the tongue or face, throat soreness, fever, burning in the eyes, purple or red skin rash spreading to the upper body including the face, blistering, peeling, skin pain.

Your doctor will not ask you to buy Aldactazide if you are already taking any of the following drugs:

• Drugs that affect potassium levels (e.g. tacrolimus, eplerenone or cyclosporine)
• Contraceptive pills containing drospirenone
• Other diuretics (e.g. amiloride or triamterene)
• ACE inhibitors (e.g. captopril or benazepril)
• Angiotensin receptor antagonists (e.g. valsartan or losartan)
• Corticosteroids (e.g. prednisone)
• Medicines that may increase blood pressure (e.g. phenylephrine or pseudoephedrine)

Warnings & Precautions of Aldactazide

Do not use Aldactazide if you have kidney disease, hyperkalemia or inability to urinate. Also inform your doctor beforehand if you have a heart disease, diabetes, liver disease such as cirrhosis, glaucoma, gout, lupus, breathing disorder, or pancreatic disorder.

Aldactazide is not meant to be used by breastfeeding mothers, as it may pass into breast milk and cause harm to the nursing infant. If taking the drug is necessary, you should stop breastfeeding the child temporarily during Aldactazide treatment.