Nurofen (Ibuprofen) and/or equivalents
Generic Nurofen Gel 0.5%Source Country: United Kingdom
Shipped From: United Kingdom Manufacturer: MHRA approved UK Generic Manufacturer
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Description of Nurofen
Nurofen falls in the category of the anti-inflammatory drugs or the analgesics. The generic name for Nurofen is Ibuprofen. One can buy Nurofen in the form of tablets and suspension. Nurofen tablets are sold in the form of 100 mg, 200 mg, 400 and 600 mg strength tablets. The suspension is usually available as 100mg/5 ml and in used for infants and children. Nurofen is a nonsteroidal anti-inflammatory (NSAID) and antipyretic. It is prescribed as per the weight of a person. For infants and children, it is administered in the form of a suspension ranging from a 2.5 ml dose to a 5 ml dose spread over 24 hours depending on the patient’s weight.
Indications & Dosage of Nurofen
Nurofen acts as an anti-inflammatory agent and relieves pain and the swelling in the muscles. It also reduces the body temperature of the person suffering from fever as it is an antipyretic.
The exact mechanism or action of the drug is still unknown. However, it is believed that Nurofen inhibits the synthesis of prostaglandins, which are the chemical messengers that work in a cell. Prostaglandins cause inflammation, fever and pain. Nurofen stops the formation of prostaglandins and reduces pain and fever. Cyclooxygenase 1 and Cyclooxygenase 2 are the enzymes required for the production of prostaglandins. Nurofen inhibits the formation of prostaglandins by interfering with the enzyme Cyclooxygenase1 1 and 2 that are required for prostaglandin synthesis.
Nurofen can be used for treating flu symptoms, fever, muscle pain, tooth ache, menstrual cramps, rheumatoid arthritis and osteoarthritis. Children over the age of 12 and adults can begin with a dose of 200 mg to 400 mg for not more than 3 times a day, with a gap of 4 hours between the doses. One should be careful not to exceed 1200 mg a day. The tablets should be taken with water after meals. One should not lie down for about 30 to 60 minutes after taking the dose to avoid esophageal irritation. Consult a doctor if the symptoms do not disappear within 3 to 4 days.
Side Effects & Interactions of Nurofen
As seen in the case of many drugs, certain moderate to mild side effects have been observed with Nurofen. Some common side effects of the drug are :
- Stomach pain
- Increased heart rate
- Blurred vision
Gastrointestinal disorders like dyspepsia, peptic ulcers, or bleeding can also occur in some patients. Patients suffering from heredity digestive disorders such as problems digesting certain sugars like fructose, and glucose-galactose should avoid this drug. Patients suffering from a deficiency of the enzyme sucrase-isomaltase should not take Nurofen.
Interaction of Nurofen is seen with many other classes/drugs :
Warnings & Precautions of Nurofen
Patients hypersensitive to other nonsteroidal and anti-inflammatory drugs should not buy Nurofen. Nurofen should also not be used by patients suffering from hepatic failure and heart failure. There is a possibility of renal function being impaired due to the use of Nurofen.
Female fertility can be impaired by the use of Nurofen, but this is reversible the treatment is withdrawn.
Pregnant and nursing mothers should not buy Nurofen as it can harm a fetus and nursing child.