Letairis Ambrisentan and/or alternatives

Product / Manufacturer
Quantity / Price (USD)

Ambrisentan 5mg

Generic Alternative to Letairis 5mg
Marketed as Pulmonext 5 in India Manufacturer: MSN Source Country : India
Shipped from : India

Ambrisentan 5mg

Generic Alternative to Letairis 5mg
Manufacturer: Viatris Pty Ltd Source Country : New Zealand
Shipped from : New Zealand

Ambrisentan 10mg

Generic Alternative to Letairis 10mg
Marketed as Pulmonext 10 in India Manufacturer: MSN Source Country : India
Shipped from : India

Ambrisentan 10mg

Generic Alternative to Letairis 10mg
Manufacturer: Viatris Pty Ltd Source Country : New Zealand
Shipped from : New Zealand
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  • This item requires a prescription from your doctor

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Description of Letairis

Letairis is a medicine used in the treatment of pulmonary arterial hypertension (PAH) which contains the active ingredient ambrisentan. Endothelins are proteins that increase blood pressure by constricting the blood vessels. Letairis works by blocking the release of this protein into the bloodstream.

Ambrisentan (as Letairis is generically called) is available in two different strengths: Letairis 5mg and Letairis 10mg oral tablets. The inactive constituents of this medicine are: lactose monohydrate, microcrystalline cellulose, croscarmellose sodium and magnesium stearate.

Indications & Dosage of Letairis

The primary function of Letairis is the treatment of pulmonary (artery) hypertension (or PAH) in adults. This disorder relates to extremely high blood pressure in the arteries connected to the lungs.

Letairis should be administered exactly as prescribed by the doctor. Dosages are highly individualized based on the requirements, medical history, and other medications of patients. However, Letairis can be initiated with 5mg tablets and eventually increased up to 10mg as per the doctor’s discretion.

Patients who buy Letairis should be very particular about not overdosing on this medicine. If such an incident occurs, emergency medical aid should be sought. Letairis tablets should be swallowed whole. This medicine should be stored at temperatures ranging between 15 and 30 degrees Celsius.

Side Effects & Interactions of Letairis

Side effects that are experienced during Letairis therapy more often than not are indicative of serious health issues that may be caused due to the drug. Some of them are common and not as severe as others. However, such side effects should be reported to the doctor if they worsen. A few of the common side effects of Letairis are:

  • Headache
  • Sinusitis, nasal blockage
  • Swelling of body parts like feet, ankles and limbs
  • Stomach problems like constipation, pain
  • Nose or throat sores
  • Hot flashes
  • Wheezing, increased heart beat

Some of the serious side effects of Letairis are listed below. The first five may be symptoms of liver damage.

  • Nausea, vomiting and appetite loss
  • Severe abdominal pain, general body ache
  • Itchiness
  • Fever, weakness, flu symptoms
  • Yellowing of skin and eyes, dark urine
  • Unexpected weight gain, fatigue and persistent swelling of body parts (indicating fluid retention in the body)
  • Sperm count reduction
  • Reduced levels of red blood cells

Patients should consult the doctor at regular intervals and undergo check-ups during the first few months of using Letairis.

It is of utmost importance that the doctor is made aware of all drugs (prescription, OTC, cosmetic, herbal) that are being used by patients to reduce the harmful effects of drug interactions in the body. Some drugs that are known to interact with Letairis are: cyclosporine, tizanidine, leflunomide, ritonavir, methotrexate, rifampin and verteporfin. Patients should never stop or begin to use any drug, including Letairis without prior approval from the doctor.

Warnings & Precautions of Letairis

Letairis is a pregnancy category X drug. It can potentially cause birth defects in the child or lead to fetal death. Letairis is not recommended for use by nursing women.

This drug may interfere with the effectiveness of contraceptives.



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