Depakote ER (Divalproex Sodium ER) and/or equivalents

Product / Manufacturer Quantity / Price (USD)

Depakote ER 250mg Source Country: United States Shipped From: United States Manufacturer: Abbott Laboratories

100 tablets - $244.00

Depakote XR 250mg Source Country: India Shipped From: India Marketed as Depakote XR in India Manufacturer: Sanofi Aventis

150 tablets - $75.00 300 tablets - $135.00 450 tablets - $185.00 600 tablets - $225.00

Depakote XR 500mg Source Country: India Shipped From: India Marketed as Depakote XR in India Manufacturer: Sanofi Aventis

150 tablets - $99.00 300 tablets - $185.00 450 tablets - $255.00 600 tablets - $325.00

Generic Divalproex Sodium ER 250mg Source Country: United States Shipped From: United States Manufacturer: US FDA Generic

100 tablets - $51.00 200 tablets - $93.00 300 tablets - $135.00 400 tablets - $177.00

Generic Divalproex Sodium ER 250mg Source Country: India Shipped From: India Manufacturer: Torrent

100 tablets - $29.00 200 tablets - $49.00 300 tablets - $69.00 400 tablets - $85.00

Generic Divalproex Sodium ER 500mg Source Country: United States Shipped From: United States Manufacturer: US FDA Generic

100 tablets - $40.00 200 tablets - $75.00 300 tablets - $99.00

Generic Divalproex Sodium ER 500mg Source Country: India Shipped From: India Manufacturer: Torrent

100 tablets - $40.00 200 tablets - $75.00 300 tablets - $99.00

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• This item requires a prescription from your doctor


• What is a Generic?

Description of Depakote ER

Depakote ER is used to treat Bipolar Affective Disorder or maniac depression. Its generic name is Divalproex Sodium. Depakote ER is a mood stabilizer and belongs to a class of Anticonvulsants.

The communication of brain and nerves is kept balanced by a hormone in the brain called GABA that acts as a natural calming agent. When GABA reduces, it over-stimulates the brain. Depakote ER enables increased supply of GABA to the brain to calm the nerve cells for a longer period of time. Thus, it stabilizes the electrical nerve activity in the brain and calms the period of mania. The available strengths are: Depakote ER 250 mg and Depakote ER 500mg.It is administered in the form of oral tablets.

Indications & Dosage of Depakote ER

The recommended dosage for mania is 25mg/kg/day given once daily. The dose should be increased rapidly to reach the dose which yields the desired clinical effect. The maximum recommended dosage is 60mg/kg/day.

The recommended dose for migraine is 500mg/day once daily for 1 week, increased to a maximum of 1000mg/day.

Due to somnolence in the elderly, their dosage should be lighter in the beginning, preferably 250mg/day. It should be increased slowly by increasing the intake of fluids and nutritional food. Store the tablets at 25 degrees Celsius.

Side Effects & Interactions of Depakote ER

Before you buy Depakote ER, tell your doctor if you are allergic to any of its ingredients. This medication should not be used if you have certain medical conditions such as pancreatitis, liver disease, metabolic disorder, etc.

Before using Depakote ER, tell your doctor about your medical history, especially of alcohol abuse, kidney disease, brain disease (Dementia), bleeding problems, and dehydration.

Some of the less serious side effects of Depakote ER are :

• Diarrhea, constipation
• Mild drowsiness or weakness
• Changes in menstrual periods
• Tremors(shaking)
• Enlarged breasts, weight changes
• Unusual taste in your mouth
• Vision changes
• Hair loss

The serious side effects are:

• Easy bruising, blood in the urine
• Urinating less than usual
• Fever, chills, swollen glands, body aches, flu symptoms
• Weakness with vomiting and fainting
• Double vision
• Extreme drowsiness, hallucinations
• Severe skin reaction

The drugs that interact with Depakote ER are:

• Aspirin
• Tolbutamide
• Zidovudine
• Topiramate
• Warfarin
• Diazepam
• Rifampin
• Acetaminophen
• Meropenem
• Clozapine
• Ethosuximide

Warnings & Precautions of Depakote ER

Before you buy Depakote ER, you must inform your doctor if you are pregnant, as using Depakote ER during pregnancy can cause congenital malformations in the fetus. Drink plenty of water while taking the medication. If the water level in your body decreases, the dosage might be decreased. Your liver functioning should be checked regularly to make sure Depakote ER is not causing any harmful reactions in the body.

Drinking alcohol can increase certain side effects. Depakote ER may impair your thinking or reactions. Avoid exposure to tanning beds and sunlight.