Combigan Brimonidine Tartrate/Timolol Maleate and/or alternatives

Product / Manufacturer
Quantity / Price (USD)

Combigan 0.2%/0.5%

Manufacturer: Allergan Source Country : India
Shipped from : India

Combigan 0.2%/0.5%

Manufacturer: Allergan Inc. Source Country : United Kingdom
Shipped from : United Kingdom

Brimonidine Tartrate/Timolol Maleate 0.2%/0.5%

Generic Alternative to Combigan 0.2%/0.5%
Marketed as Brimocom in India Manufacturer: Cipla Source Country : India
Shipped from : India
  • What is a Generic?

  • This item requires a prescription from your doctor

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  • Please note that the source country, shipping country and/or manufacture may vary depending on availability.

Description of Combigan

Combigan is a combination medicine that contains Timolol and Brimonidine. Timolol falls under the category of beta blockers, which are helpful in reducing pressure inside the patient’s eyes. Brimonidine belongs to the class of alpha-agonists, which reduce the amount of fluids in the eyes. This helps decrease pressure inside the patient’s eyes.

You can buy Combigan in the form of an ophthalmic solution.

Indications & Dosage of Combigan

Combigan is an ophthalmic solution used for treating ocular hypertension or glaucoma in the eyes.

Your doctor will advise you to apply one Combigan drop into your affected eye twice a day. Try to maintain a gap of around 12 hours between each application. If you are using any other ophthalmic products along with Combigan, you should keep a gap of at least 5 minutes between them.

Combigan ophthalmic solution contains 2mg/ml Brimonidine and 5mg/ml Timolol.

Side Effects & Interactions of Combigan

Side effects commonly experienced by Combigan patients include:

  • Mild burning, itching or stinging in the eyes
  • Blurred vision or dry eyes
  • Puffy or swollen eyes
  • Feeling like there is something in the eye
  • Weakness or tiredness
  • Cough and throat soreness
  • Headache
  • Nausea and stomach upset
  • Drowsiness
  • Increased sensitivity to light
  • Dry nose
  • Unpleasant or unusual taste in the mouth

These are mild side effects of the drug and subside over time. However, you should seek medical attention if any of these become too bothersome.

Seek medical help immediately if you have any serious side effects after using Combigan. Such symptoms include:

  • Bronchospasms (chest tightness, wheezing, and trouble breathing)
  • Severe discomfort, pain, burning, itching or swelling in or around the eye
  • Fluttering in the chest or pounding heartbeat
  • Weak pulse, slow heart rate, slow breathing or fainting
  • Cold feeling, numbness, or tingling in the feet or hands
  • Muscle weakness
  • Hallucinations, confusion, or unusual behavior or thoughts

Taking Combigan along with certain other medicines may also lead to drug interactions and may sometimes cause serious complications. Some of the drugs you should avoid taking during Combigan treatment include:

  • Antidepressants
  • Blood pressure medicines
  • HIV or AIDS medicines (e.g. ritonavir)
  • Antihistamines (e.g. diphenhydramine)
  • Antifungal drugs (e.g. terbinafine)
  • Anti-malaria medicines (e.g. hydroxychloroquine)
  • Drugs for treating psychiatric disorders (e.g. thioridazine)
  • Heart rhythm drugs (e.g. propafenone or quinidine)
  • Calcium channel blockers (e.g. amlodipine or diltiazem)
  • Other beta blockers (e.g. atenolol or metoprolol)

Warnings & Precautions of Combigan

Your doctor will not recommend you to buy Combigan if you have asthma, heart disease, AV block, slow heartbeat, heart failure, or COPD. He or she will need to conduct some special tests if you are suffering from diabetes, an overactive thyroid, depression, circulation problems (e.g. Buerger’s disease or Raynaud’s syndrome), muscle disorder (e.g. myasthenia gravis), or if you have a history of low blood pressure or fainting.

Pregnant women and breastfeeding mothers should not take Combigan, as it may cause harm to the unborn child or nursing baby.



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