Diacomit Stiripentol and/or alternatives

Product / Manufacturer
Quantity / Price (USD)

Diacomit 500mg

Manufacturer: Alan Pharmaceuticals Source Country : United Kingdom
Shipped from : United Kingdom

Diacomit 250mg

Manufacturer: Biocodex Canada Inc. Source Country : Canada

This product is currently unavailable.

  • This item requires a prescription from your doctor

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Description of Diacomit

Diacomit is used to treat a very rare type of epilepsy in children called Severe Myoclonic epilepsy in Infancy (SMEI) or Dravetas Syndrome. It is an anti-epileptic medicine. Diacomitis used along with Clobazam and Valproate when they fail to control generalized tonic-clonic seizures. The generic name of this medication is Stiripentol, an active ingredient.

Diacomit is available in the form of capsules and sachets (containing a powder for oral suspension) in two strengths: Diacomit 250mg and Diacomit 500mg. You cannot buy Diacomit without a doctor’s prescription.

It is advisable to administer Diacomit under the supervision of a pediatrician who has sufficient experience in diagnosing and managing epilepsy in infants and children. The dose must be taken exactly as prescribed by the doctor.

Indications & Dosage of Diacomit

The dosage of Diacomit is influenced by the patient’s weight. The normal dose is 50 mg/kg weight. It is advisable to administer a daily dose in 2 or 3 divided doses. The capsule is taken with a glass of water during a meal, as it degrades rapidly in an acidic environment. You need to mix the required amount of Diacomit powder into a glass of water. You can then drink the mixture while you are having a meal. Please remember, however, that the mixture should be made only immediately before consuming it. Do not make the mixture and store it for later consumption. It is not advisable to consume carbonated drinks, caffeine, milk or dairy products, fruit juice or theophylline with Diacomit. Treatment usually begins with a low dose, which gradually increases to the recommended dose over a period of three days. You may need to increase or decrease the dosage of Clobazam and Valproate while using Diacomit.

It is important that Diacomit is taken regularly at the same time each day. If you miss a dose, take it as soon as you remember unless it is time for the next dose.

Side Effects & Interactions of Diacomit

The most common side effects of Diacomit are:

  • Loss of appetite
  • Loss of weight
  • Weakness in the muscles
  • Drowsiness
  • Muscle disorders
  • Insomnia
  • Loss of weight
  • Difficulty coordinating muscle movements
  • Raised levels of liver enzymes
  • irritability, aggression, hyper-excitability, agitation

The drugs that interact with Diacomit are:

  • Ergotamine
  • Cisapride
  • Halofantrine
  • Tacrolimus
  • Sirolimus
  • Simvastatin
  • Chlorpromazine
  • Midazolam

You must inform the doctor about all the other drugs you are using. Such drug interactions lead to severe consequences such as decreased hepatic metabolism of the cholesterol-lowering agent, toxicity etc.

Warnings & Precautions of Diacomit

You must inform your doctor if you have impaired hepatic and/or renal function. If you are pregnant, do not cease anticonvulsant treatment as worsening of the disease can prove dangerous for both the mother and fetus. Breastfeeding is not recommended during Diacomit treatment. You should not buy Diacomit if you are hypersensitive to Stiripentol or to any of the other ingredients. If a patient has a history of psychosis accompanied with delirium, the drug should not be used. Care must be taken when Diacomit is used along with other medicines.

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