Exjade Deferasirox and/or alternatives

Product / Manufacturer
Quantity / Price (USD)

Exjade 125mg

Manufacturer: Novartis Source Country : Turkey
Shipped from : Turkey

Exjade 250mg

Manufacturer: Novartis Source Country : Turkey
Shipped from : Turkey

Exjade 500mg

Manufacturer: Novartis Source Country : Turkey
Shipped from : Turkey

Deferasirox 125mg

Generic Alternative to Exjade 125mg
Marketed as Apo-Deferasirox in Canada Manufacturer: Apotex Corporation Source Country : Canada
Shipped from : Canada

Deferasirox 250mg

Generic Alternative to Exjade 250mg
Marketed as Defrijet in India Manufacturer: Sun Pharma Source Country : India
Shipped from : India

Deferasirox 500mg

Generic Alternative to Exjade 500mg
Marketed as Defrijet in India Manufacturer: Sun Pharma Source Country : India
Shipped from : India
  • What is a Generic?

  • This item requires a prescription from your doctor

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  • Please note that the source country, shipping country and/or manufacture may vary depending on availability.

Description of Exjade

Deferasirox is the generic name of Exjade and it is known to be an iron chelating agent. The inactive ingredients in Exjade include povidone, Lactose monohydrate, sodium lauryl sulphate, crospovidone, silicon dioxide, microcrystalline cellulose, and magnesium stearate. Exjade is available in the form of oral tablets and the composition includes 125 mg, 250 mg, or 500 mg of deferasirox. You can buy Exjade from a pharmacy if it has been prescribed to you by your physician.

Indications & Dosage of Exjade

Exjade is prescribed by doctors for treatment of chronic iron overload caused by blood transfusions or transfusional hemosiderosis. It is prescribed to patients over the age of 2 years and it helps in reducing the serum ferritin levels as well as the concentration of liver iron.

The recommended starting dose is Exjade 20 mg/kg of your body weight. This oral medication needs to be administered once a day and on an empty stomach. You need to ensure that there is a 30 minute gap between intake of the medicine and your previous meal or next meal. You can take Exjade with water or with orange or apple juice. You need to take Exjade 20 mg/kg at the same time every day. The dose can be adjusted depending on the serum ferritin and serum creatinine levels. Adjustment dose for serum ferritin should be administered after 3-6 months of initial Exjade therapy. The adjustments should be made in steps of Exjade 5 mg/kg or 10 mg/kg and the maximum dose should not be over 40 mg/kg.

Side Effects & Interactions of Exjade

Administration of Exjade can lead to mild or moderate side effects with clearly visible symptoms. Some of the most common side effects include:

  • Diarrhea
  • Nausea
  • Stomach pain
  • Vomiting
  • Rashes and hives
  • Swelling of the mouth and face
  • Swelling of lips
  • Unusual hoarseness
  • Tightness in the chest
  • Yellowing of the skin

There are some adverse effects of administration of Exjade and if you see the following symptoms then discontinue the treatment and inform your doctor.

  • Dark urine and pale stools
  • Decreased vision or blurred vision
  • Persistent sore throat followed by severe cough
  • Unusual bruising and even bleeding
  • Loss of hearing and other hearing problems
  • Non-fatal gastrointestinal bleedings
  • Renal and hepatic failure
  • Pharyngitis and rhinitis
  • Intermittent proteinuria
  • Renal tubulopathy
  • Agranulocytosis and neutropenia

Exjade is known to interact with other drugs including ibuprofen, urokinase, tenofovir, magnesium hydroxide, aspirin, salicylamide, pamabrom, risedronate, ketoprofen, betamethasone, and pseudoephedrine among others.

Warnings & Precautions of Exjade

Clinical studies conducted on animals have revealed that Exjade can harm the fetus and can cause embryo fetotoxicity, which is an increase in renal anomalies in the unborn. There is no data available to support if Exjade or any ingredient is secreted through human milk but most doctors advise against taking this medicine during pregnancy or breast feeding. Some of the other precautions to take is not to miss your dose and never buy Exjade tablets that are beyond the expiry date.

You need to discuss your medical history with the doctor prior to beginning Exjade medication. You need to inform your doctor if you have the following :

  • If you are taking antacids like Maalox, Mi-Acid, and Rulox
  • Severe kidney disease
  • Advanced cancer stage
  • Blood cell disorder
  • History of intestinal bleeding

Exjade should not be administered to patients who have a weak immune system and already taking medications for the same.



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