Florinef Fludrocortisone Acetate and/or alternatives

Product / Manufacturer
Quantity / Price (USD)

Florinef 0.1mg

Manufacturer: Paladin Labs Inc. Source Country : Canada
Shipped from : Canada

  • This item requires a prescription from your doctor

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  • Please note that the source country, shipping country and/or manufacture may vary depending on availability.

Description of Florinef

Fludrocortisone acetate is the generic name of Florinef and it is prescribed for oral administration only. Fludrocortisone acetate is considered as a synthetic adrenocortical steroid. The inactive ingredients in Florinef include corn starch, calcium phosphate, magnesium stearate, lactose, talc, and sodium benzoate. You can buy Florinef only if it has been prescribed for administration by your doctor.

Indications & Dosage of Florinef

Florinef is prescribed by doctors as a medication in partial replacement therapy to treat both primary and secondary adrenocortical insufficiency as noticed in Addison’s disease. It is also used for treatment of salt-losing adrenogenital syndrome.

The dosage of Florinef will vary from one patient to another and is primarily dependent on the severity of the medical condition as well as the response of patients towards this medicine. Patients suffering from Addison's disease are prescribed Florinef tablets along with glucocorticoids like cortisone or hydrocortisone to assist in the substitution therapy.

The standard recommended dose is Florinef 0.1 mg daily. The dosage can be reduced to Florinef 0.05 mg if the patient develops transient hypertension. Depending on the condition, doctors can also recommend Florinef 0.1 mg dose thrice a week or 0.2 mg once every day.

The recommended standard dose for patients suffering from salt-losing adrenogenital syndrome is Florinef 0.1 mg to 0.2 mg once every day. These tablets are available in bottles of 100 and should be stored in room temperature and away from heat.

Side Effects & Interactions of Florinef

Administration of Florinef can lead to mild or moderate side effects with clearly visible symptoms. Some of the most common side effects include:

  • Difficulty sleeping or insomnia
  • Lightheadedness, drowsiness, or dizziness
  • Mild to severe headache
  • Increased appetite
  • Increased sweating
  • Stomach problems and indigestion
  • Allergic reactions like rashes and hives
  • Swelling of the mouth
  • Feeling of tightness in the chest

There are some adverse effects of administration of Florinef and if you see the following symptoms then discontinue the treatment and inform your doctor.

  • Pain in the bone or joints
  • Sudden mood changes including depression and anxiety
  • Muscle weakness and pain
  • Nausea and vomiting
  • Swelling of legs and feet
  • Changes in vision
  • Cardiac enlargement and congestive heart failure
  • Ulcerative esophagitis, Pancreatitis, and gastrointestinal perforation
  • Adrenal suppression, hyperglycemia, and cushingoid appearance
  • Negative nitrogen balance

Florinef is known to interact with other drugs like adalimumab, amiodarone, moxifloxacin, arsenic trioxide, leflunomide, bupropion, cinoxacin, ciprofloxacin, dofetilide, dronedarone, and etanercept among others.

Warnings & Precautions of Florinef

You cannot buy Florinef if you are pregnant. Although there is no data available to prove that this medicine is harmful but it is definitely not recommended for pregnant women. If you are breastfeeding or planning pregnancy then discuss the same with your doctor before starting Florinef therapy.

Administration of Florinef can lead to masking of certain infections in the human body. Hence, it is advisable to discuss your current and past medical problems with the doctor. If you are on corticosteroid therapy then avoid smallpox vaccination.

You need to discuss your medical history with the doctor prior to beginning Florinef medication. You need to inform your doctor if you have the following :

  • If you are taking immunosuppressant drugs
  • If you have active tuberculosis
  • If you have hypothyroidism or cirrhosis
  • If you are taking aspirin


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