Oforta Fludarabine Phosphate and/or alternatives
Fludara 10mgManufacturer: Genzyme Canada Inc. Source Country : Canada
Shipped from : Canada
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Description of Oforta
Fludarabine phosphate is the generic name of Oforta and it is available in the form of tablets for oral use. Each tablet of Oforta contains 10 mg of Fludarabine phosphate. Some of the other ingredients of Oforta include lactose monohydrate, microcrystalline cellulose, croscarmellose sodium, colloidal anhydrous silicon dioxide, magnesium stearate, hypromellose, titanium dioxide (E171), talc, and ferric oxide pigment. You can buy Oforta from a drug store or pharmacy by showing your prescription.
Indications & Dosage of Oforta
Oforta is administered for treating those patients who have B-cell chronic lymphocytic leukemia (CLL). It is a cancer medication and works by interfering with the growth of the cancer cells and stops them from spreading in the human body. It can be administered as a standalone medicine but most doctors prefer to administer Oforta along with other cancer medications.
The recommended initial dose for adults is Oforta 40 mg/m taken orally for 5 consecutive days. You can take Oforta with or without food but it needs to be swallowed whole with a glass of water. There should be a minimum gap of 28 days between two 5-day treatments. The administration of Oforta is dependent on the Body Surface Area or BSA. The maximum dosage for adults with BSA of 2.39 to 2.50 is Oforta 100 mg or 10 tablets and those with a BSA of 0.75 to 0.88 is Oforta 30 mg or 3 tablets.
Side Effects & Interactions of Oforta
Administration of Oforta can lead to mild or moderate side effects with clearly visible symptoms. Some of the most common side effects include:
- Pale yellow skin
- Dark colored urine
- Slow or fast heart rate
- Unusual bleeding through mouth, nose, rectum, or vagina
- Symptoms of the flu
- Sores in throat or mouth
- Green or yellow mucus with cough
- Stabbing chest pain
- Blood in Urine
- Burning sensation while urinating
- Blood in cough
- Less frequent urination
- Purple pinpoint spots under skin
- Muscle pain and swelling in legs
There are some adverse effects of administration of Oforta and if you see the following symptoms then discontinue the treatment and inform your doctor.
- Bone marrow suppression
- Neutropenia and thrombocytopenia
- Cumulative myelosuppression
- Trilineage bone marrow hypoplasia
- Autoimmune hemolytic anemia
- Pulmonary toxicity
- Tumor lysis syndrome
- Renal impairment
- Hematologic and nonhematologic toxicity
Oforta is known to interact with other drugs like abraxane, brentuximab, alefacept, alemtuzumab, amiodarone, metronidazole, montelukast, niacin, norfloxacin, ofloxacin, oxaliplatin, and paclitaxel among others.
Warnings & Precautions of Oforta
If you are pregnant then consult your doctor before you buy Oforta. Oforta is known to harm the fetus and its administration can lead to decreased fetal body weight, visceral malformation, skeletal malformation, decrease in live fetus, and an increase in resorption. It is not known if Oforta is secreted through human milk but it is advised to consult your doctor if you are breastfeeding.
You need to discuss your medical history with the doctor prior to beginning Oforta medication. You need to inform your doctor if you have the following :
- If you have some form of kidney disease
- If you have a weak immune system
- If you are taking pentostatin
- If you have bone marrow problems