Sintrom Nicoumalone and/or alternatives
Sintrom 1mgMarketed as Sinthrome in European Union Manufacturer: Alliance Pharmaceuticals Ltd Source Country : United Kingdom
Shipped from : United Kingdom
Sintrom 4mgManufacturer: Paladin Labs Inc. Source Country : Canada
Shipped from : Canada
Nicoumalone 1mgGeneric Alternative to Sintrom 1mg
Marketed as Acitrom in India Manufacturer: Nicholas Pharma Source Country : India
Shipped from : India
Nicoumalone 4mgGeneric Alternative to Sintrom 4mg
Marketed as Acitrom in India Manufacturer: Abbott Source Country : India
Shipped from : India
- What is a Generic?
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Description of Sintrom
Sintrom belongs to the group of medicines known as anticoagulants or blood thinners. The active ingredient present in this drug is acenocoumarol. It is an antagonist of vitamin K and similar proteins that are responsible for forming blood clots.
Doctors may advise patients suffering from heart disorders that involve blood clotting in the arteries to buy Sintrom. This drug is available as 1mg and 4mg tablets. The generic name for Sintrom is Acenocoumarol.
Indications & Dosage of Sintrom
The primary function of Sintrom is to prevent coagulation of blood. It may be used in the treatment of the following conditions:
- Blood clotting in the veins
- A heart rhythm disorder known as atrial fibrillation.
- Ischemic attacks.
- Blood coagulation in the lungs
Patients who buy Sintrom need to strictly follow the doctor’s instructions pertaining to dosage and administration.
The dosage usually recommended for Sintrom patients lies between 8mg and 12mg daily initially. This may be adjusted and eventually maintained between 1 to 10mg daily following blood tests as conducted and assessed by the doctor.
There are certain points that require attention while administering Sintrom:
- The drug should not be taken within an hour and a half of food intake.
- Sintrom tablets should be swallowed whole with plain water.
- Beverages and food should be avoided for thirty minutes post intake.
- The patient may not lie down within half an hour of taking Sintrom
It is advisable that patients do not take part in vigorous activities that may cause injury and stay away from sharp objects to avoid cutting or bruising.
Side Effects & Interactions of Sintrom
Sintrom may potentially be responsible for some side effects in patients using this drug. Some are moderate and do not require medical attention (as the body adjusts to them over a short span) while others may pose a serious threat to health and be indicative of underlying disorders. Some common and mild side effects of Sintrom are:
- Nausea, vomiting
- Hives, rashes, itching
- Loss of hair
The list of serious side effects which should immediately be reported to the doctor includes:
- Unusual bleeding (e.g., from eyes, nose) or bruising
- Prolonged bleeding from minor wounds
- brown or pink urine
- Heavy menstrual bleeding
- Bloody stools, vomit or urine
- Swelling, pain or discomfort
There is a long list of drugs (both prescription and OTC) which should be avoided or require major dosage adjustments during Sintrom usage. It is compulsory for patients to disclose all their medications to the doctor. A few of such drugs are: acetaminophen, azithromycin, cimetidine, carbamazepine, rifampin, contraceptives, NSAIDs, phenytoin, dextran, diuretics, glucagon, narcotics and MAO inhibitors.
Warnings & Precautions of Sintrom
Acenocoumarol can pass into breast milk and cause injury to an infant. It should not be used while breastfeeding. Pregnant women must discuss the risks associated with a doctor before using this medication.
There are many medical conditions like polyarthritis, vitamin C deficiency, severe renal or liver disorders, eclampsia, hypertension and ulceration that contraindicate Sintrom usage. Patients should be particular about mentioning their current and past medical problems to their doctor before using Sintrom.